Clinical and Dermoscopic Triage of head and neck Macules: The Role of Reflectance Confocal Microscopy in a Prospective Study of 2006 Lesions

Description

Supplementary Fig 1. Workflow illustrating tumors distribution according to dermoscopic, confocal and histologic diagnoses. Supplementary Fig 2. A) Dermoscopy showing brown pseudonetwork with defined borders, interpreted as solar lentigo. B-C) Reflectance confocal microscopy (RCM) revealing LM features, specifically: B) RCM at epidermal layer showing perifollicular and interfollicular dendritic cells. C) RCM at dermal-epidermal layer showing medusa-head like structure. Supplementary Fig 3. Double negative LM case: A) Dermoscopy showing multiple grey dots. B) RCM at epidermal layer showing honeycombed pattern with focal mottled pigmentation. C) RCM at dermal-epidermal layer showing abundant melanophages. Supplementary Fig 4. Double negative BCC case: A) Dermoscopy showing brown-red background. B) RCM at epidermal layer showing honeycombed pattern with focal mottled pigmentation. C) RCM at dermal-epidermal layer showing aspecific structures.

Institutions

• IRCCS Ospedale San Raffaele

  Lombardy, Milan
• University of Modena and Reggio Emilia

  Emilia-Romagna, Modena
• Sapienza University of Rome

  Lazio, Rome
• University of Parma

  Emilia-Romagna, Parma

Categories

Funders

• Ministero della Salute

  Governo Italiano

  Rome

  Grant ID: NET-2011-02347213

Licence