Altered Frequency and Phenotype of HLA-G-Expressing DC-10 in Type 1 Diabetes Patients at Onset and in Subjects at Risk to Develop the Disease.

Published: 26 January 2022| Version 1 | DOI: 10.17632/gnf7tndkph.1
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Description

In the manuscript "Altered Frequency and Phenotype of HLA-G-Expressing DC-10 in Type 1 Diabetes Patients at Onset and in Subjects at Risk to Develop the Disease" (doi: 10.3389/fimmu.2021.750162.), we reported, for the first time, the evaluation of a population of HLA-G-expressing tolerogenic dendritic cells in the peripheral blood of T1D patients and first-degree relatives demonstrating the impairment in the number and phenotype of DC-10 is associated with the risk to T1D. The three dataset here loaded (Raw_data_1, 2, and 3) contain all the clinical and immunological data, supporting our conclusions, that have been used to build the manuscript. An additional file (raw_data_description) contains the main guidelines to correctly associate the raw data with the corresponding figure/table in the manuscript.

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Institutions

San Raffaele Telethon Institute for Gene Therapy, Ospedale San Raffaele

Categories

Patient with Type 1 Diabetes, Dendritic Cell Subset

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