Prevalence and risk factors of ellipsoid zone damage after pars plana vitrectomy for idiopathic epiretinal membrane

Published: 3 February 2022| Version 1 | DOI: 10.17632/hf4m6x5x2j.1
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Prevalence and risk factors of ellipsoid zone damage after pars plana vitrectomy for idiopathic epiretinal membrane DOI: 10.1097/IAE.0000000000003321

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Retrospective study to assess factors associated with external limiting membrane (ELM)/ellipsoid zone (EZ) damage after vitrectomy (PPV) for epiretinal membrane (ERM) and evaluate their impact on functional and anatomic outcomes. Patients who underwent PPV with ERM ± inner limiting membrane (ILM) peeling were retrospectively analyzed. Best-corrected visual acuity and central macular thickness were longitudinally collected based on available follow-up. Demographic data, clinical and surgical details were included in logistic regression models having ELM/EZ loss as a binary outcome. We found that cataract extraction during vitrectomy and the presence of outer retinal abnormalities at baseline are associated with higher odds of external limiting membrane/ellipsoid zone defects after vitrectomy. The rate of functional improvement varies as a function of the baseline visual acuity and severity of retinal layers’ distortion before surgery.

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Ospedale San Raffaele, Universita Vita Salute San Raffaele

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Ophthalmology

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